USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: UFD1_HUMAN USC-OGP 2-DE database:  UFD1_HUMAN UFD1_HUMAN General information about the entry View entry in simple text format Entry name UFD1_HUMAN Primary accession number Q92890 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Ubiquitin fusion degradation protein 1 homolog; Short=UB fusion protein 1;. Gene name Name=UFD1L Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0185: pI=4.70; Mw=26241 Cross-references UniProtKB/Swiss-Prot Q92890; UFD1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name UFD1_HUMAN Primary accession number Q92890 Secondary accession number(s) A8MW31 Q9Y5N0 Sequence was last modified on  November 13, 2007 (version 3) Annotations were last modified on  March 15, 2017 (version 144) Name and origin of the protein Description RecName: Full=Ubiquitin fusion degradation protein 1 homolog; Short=UB fusion protein 1; Gene name Name=UFD1L Encoded on Name=UFD1L Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation pathway. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U64444; AAD08720.1; -; mRNA EMBL AF141201; AAD28788.1; -; mRNA EMBL CR456607; CAG30493.1; -; mRNA EMBL AK225877; -; NOT_ANNOTATED_CDS; mRNA EMBL AC000068; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC000087; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC001049; AAH01049.1; -; mRNA EMBL BC005087; AAH05087.1; -; mRNA CCDS CCDS13761.1; -. [Q92890-2]; . CCDS CCDS33600.2; -. [Q92890-3]; . RefSeq NP_001030324.2; NM_001035247.2. [Q92890-3]; . RefSeq NP_005650.2; NM_005659.6. [Q92890-2]; . UniGene Hs.474213; -; . PDB 2YUJ; NMR; -; A=11-193 PDB 5C1B; X-ray; 3.08 A; U/V=221-241 PDBsum 2YUJ; -; . PDBsum 5C1B; -; . ProteinModelPortal Q92890; -; . SMR Q92890; -; . BioGrid 113200; 96; . DIP DIP-45954N; -; . IntAct Q92890; 32; . MINT MINT-2837704; -; . STRING 9606.ENSP00000263202; -; . iPTMnet Q92890; -; . PhosphoSitePlus Q92890; -; . BioMuta UFD1L; -; . DMDM 160332310; -; . OGP Q92890; -; . EPD Q92890; -; . PaxDb Q92890; -; . PeptideAtlas Q92890; -; . PRIDE Q92890; -; . DNASU 7353; -; . Ensembl ENST00000263202; ENSP00000263202; ENSG00000070010. [Q92890-2]; . Ensembl ENST00000399523; ENSP00000382439; ENSG00000070010. [Q92890-3]; . GeneID 7353; -; . KEGG hsa:7353; -; . UCSC uc002zpm.3; human. [Q92890-2]; . CTD 7353; -; . DisGeNET 7353; -; . GeneCards UFD1L; -; . HGNC HGNC:12520; UFD1L; . HPA HPA030287; -; . HPA HPA030288; -; . HPA HPA073425; -; . MalaCards UFD1L; -; . MIM 601754; gene; . neXtProt NX_Q92890; -; . OpenTargets ENSG00000070010; -; . Orphanet 567; 22q11.2 deletion syndrome; . PharmGKB PA37167; -; . eggNOG KOG1816; Eukaryota; . eggNOG COG5140; LUCA; . GeneTree ENSGT00390000002408; -; . HOGENOM HOG000212737; -; . HOVERGEN HBG001266; -; . InParanoid Q92890; -; . KO K14016; -; . OMA ADHSSYA; -; . OrthoDB EOG091G0KO7; -; . PhylomeDB Q92890; -; . TreeFam TF314581; -; . Reactome R-HSA-110320; Translesion Synthesis by POLH; . Reactome R-HSA-5689880; Ub-specific processing proteases; . UniPathway UPA00144; -; . ChiTaRS UFD1L; human; . EvolutionaryTrace Q92890; -; . GeneWiki UFD1L; -; . GenomeRNAi 7353; -; . PRO PR:Q92890; -; . Proteomes UP000005640; Chromosome 22; . Bgee ENSG00000070010; -; . CleanEx HS_UFD1L; -; . ExpressionAtlas Q92890; baseline and differential; . Genevisible Q92890; HS; . GO GO:0005829; C:cytosol; IEA:UniProtKB-SubCell; . GO GO:0005783; C:endoplasmic reticulum; IDA:HPA; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0036501; C:UFD1-NPL4 complex; IPI:ParkinsonsUK-UCL; . GO GO:0034098; C:VCP-NPL4-UFD1 AAA ATPase complex; IDA:UniProtKB; . GO GO:0004843; F:thiol-dependent ubiquitin-specific protease activity; TAS:ProtInc; . GO GO:0071712; P:ER-associated misfolded protein catabolic process; IMP:ParkinsonsUK-UCL; . GO GO:0070987; P:error-free translesion synthesis; TAS:Reactome; . GO GO:0039536; P:negative regulation of RIG-I signaling pathway; IMP:UniProtKB; . GO GO:0032480; P:negative regulation of type I interferon production; IMP:UniProtKB; . GO GO:0016579; P:protein deubiquitination; TAS:Reactome; . GO GO:0030970; P:retrograde protein transport; ER to cytosol; IMP:ParkinsonsUK-UCL GO GO:0001501; P:skeletal system development; TAS:ProtInc; . GO GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB; . InterPro IPR004854; UFD1; . PANTHER PTHR12555; PTHR12555; 1; . Pfam PF03152; UFD1; 1; .

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